Idiopathic Thrombocytopenic Purpura (lTP) in C~ildl'en
نویسندگان
چکیده
(7.5 mg/kg for 4 days) are the Ifest treatments to reach quickly safe platelet levels 2:30 x 109/L (3-6 days) and 'CR (7-11 days). Among non-responding (NR) patients, seven have been splenectomized and three reached stable CR. These results emphasize differences with adult ITP. Pediatr Blood Cancer 2006i47:665-667. @ 2006 Wiley-Liss, Ine. Idiopathic thrombocytopenic purpura in children remits spontaneously in the majority of cases but most children require treatment. Between 1995 and 2005, 265 children (0-15 years old) have been consecutively observed and treated: 28 children with high doses of methylprednisolone (HDMP) (15 mg/kg x 4 days), 63 with HDMP (7.5 mg/kg x 4 days), 37 with HD dexamethasone (DXM)pulses, 29 with low doses of MP, and 51 with different doses of intravenous immunoglobulins (lVIG) (0.4 or 0.8 g/kg). Fifty-seven children have not been treated because of a platelet count 2:10x 109/Land no significant bleeding. Two hundred forty-four (92.1%) children
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